A Regenerative Cocktail: Combination of Drugs Promotes the Conversion of Glial Cells to Neurons

Posted Posted in Biology, Book Review, Neurobiology

By Reshma Kolala, Biochemistry & Molecular Biology ‘22 Author’s Note: While browsing recent findings in Neuroscience, I came across research investigating the possible conversion of glia to neurons. Although the conventional idea that neurons are irreplaceable has been overturned in multiple research studies, I was immediately intrigued by the possibility for neighboring glia to be the source of neural regeneration. The implications of this research could completely transform how treatment is approached in the neuroscience field of medicine.

This is Your Brain on Music

Posted Posted in Biology, Book Review, Neurobiology

By Timur Katsnelson, Neurobiology, Physiology, and Behavior, ‘19 Author’s Note: Like everyone else, I love music- especially the works of my favorite artists. There is nothing better than listening or jamming out to your favorite song. The human love for music is a powerful binding force, but why do we even like it? What are the underlying physiological responses of our enjoyment? I wanted to explore the functions of our brain as they relate to enjoying music, and found some interesting results about what scientists have uncovered thus far.   One of the most distinguishing characteristics of the human brain is the ability to interpret and feel emotions regarding complex environmental stimuli such as visual arts and music. Even more […]

Erasing Cue-Associated Memories

Posted Posted in Biology, Health and Medicine, Neurobiology

By Neha Madugala, Cognitive Science, ‘22 Author’s Note: While working on a different paper, I became interested in treatment and therapy for drug addiction. Addiction continues to increase, yet there seem to be limited viable options to actually overcome this problem. One of the main issues in the recovery process is relapses. I found this study interesting and promising for drug therapy because it directly targets relapses, an important step in preventing and treating drug addiction more effectively.

“Gut Feeling”: How Does Modulation of Gut Microbiome Affect Depression Pathophysiology and Status?

Posted Posted in Biology, Book Review, Neurobiology

By Raida Aldosari, Nutrition Science (Biology option) ’18 Author’s Note: I wrote this literature review as part of my UWP 104F class with Dr. Lisa Sperber. The assignment was to choose a clinically-relevant topic, review the existing body of literature on this topic, and choose a specific area to write on. My topic of interest was about the relationship between gut microbiome and the brain. I became interested in this topic after reading an article about the differences between the microbial composition of individuals with depression. By the end of the quarter, my research question evolved from “how does our diet affect our brain or mood?” to “how does modulation of gut microbiome affect depression pathophysiology?” I enjoyed the flexibility of the […]

Cause of Seizures in Individuals with Angelman Syndrome

Posted Posted in Biology, Genetics, Neurobiology, News

By Neha Madugala, Cognitive Science, ‘22 Author’s Note While browsing recent scientific achievements and breaking news in the scientific community, I came across an article declaring that the 125-year-old neuroscience mystery surrounding perineuronal nets (PNNs) is finally resolved. PNNs have stumped neuroscientists for decades, yet their importance is undeniable. To understand the extent of this discovery, I read more about PNNs and found that they have a key connection to Angelman syndrome, which causes severe epileptic seizures in children. The new findings from the Philpot Lab identifying the purpose of PNNs draw a connection between PNNs and seizures, and this information can lead to improved medications and therapeutic treatment methods.

Neural Mechanisms of Axon Degradation

Posted Posted in Biology, Neurobiology

By Timur Katsnelson, Neurobiology, Physiology, and Behavior, ‘19 Author’s Note This topic was brought up during our discussion on the development of the nervous system in my neurobiology foundations class. I found it to be interesting because of its significance in the earliest stages of our lives. Further research into scientific literature discussing the role of pruning in neurodevelopment led me to learn more about its mechanism, distinctions from other forms of axon degrading, and its use in adult organisms.