CD47-SIRPα Pathway as a Target for Cancer Therapeutics

Posted Posted in Biology, Cell Biology

By: Nicholas Garaffo, Biochemistry and Molecular Biology, 20’ Authors’ Note: I originally wrote this piece for my UWP 104E class Writing in the Science’s, but I have since expanded my topic and complicated my original analysis. Ultimately, I submitted this piece to the Norman J. Lang Prize, was awarded second place, and presented my research to the UC Davis college […]

Finding a Solution in the Source: Exploring the Potential for Early Beta Cell Proliferation to Disrupt Autoreactive Tendencies in a Type 1 Diabetes Model

Posted Posted in Biology, Cell Biology, Health and Medicine

By Reshma Kolala, Biochemistry & Molecular Biology ‘22 Residing in the pancreas are clusters of specialized cells, namely alpha, beta (), and delta cells. cells, more specifically, are insulin-secreting cells that are instrumental in the body’s glucose regulation mechanism. An elevation of the extracellular glucose concentrations allows glucose to enter cells via GLUT2 transporters, where it is subsequently metabolized. The resultant […]

Recent Efforts Toward Engineering Anticancer Plant Secondary Metabolites

Posted Posted in Biochemistry, Biology, Book Review, Cell Biology

By Roxanna Pignolet, Biochemistry & Molecular Biology, ‘20 Author’s note: This literature review was originally written as an assignment for my 102B Writing in the Disciplines: Biological Sciences class. At the start of this quarter I was lucky enough to get involved in plant metabolic engineering research in Dr. Patrick Shih’s laboratory, which exposed me to the field of synthetic […]