Stem Cells: Miracle Cure or Hoax? A Review of Present Application and Potential Uses of Stem Cells

Posted Posted in Biology, Genetics, Science and Society

By Vita Quintanilla, Genetics 23’
Author’s Note: My purpose in writing this piece is to educate the current safe applications of stem cell as misuse and damage due to the same is so prevalent in the US and abroad. While not detracting from the great advances being made in the field currently this piece is to take stock of the reality of this treatment.

You might have to use more than a microscope, there’s more to genetics than what meets the eye: An interview with Dr. Gerald Quon

Posted Posted in Biology, Campus News and Reports, Genetics

By Tannavee Kumar, Genetics & Genomics 20’
Author’s Note: As an undergraduate studying genetics and genomics and computer science, I wanted to interview a former professor to find out the steps he took in order to do computational research in the biological sciences. I was interested in finding out more about the growing field of computational biology and wanted to help shed light on a field to students that may be similarly interested.

Reading into the Future: Development of Long-read DNA Sequencing

Posted Posted in Biology, Genetics

By Aditi Goyal, Genetics and Genomics, ‘22 At this moment, the next revolution in the field of biology is currently underway: third-generation sequencing, or Long-Read sequencing. Instead of relying on cluster-based short read technology (1), third-generation sequencing builds a DNA sequence on a nucleotide basis, therefore eliminating the extensive process of read alignment. Until now, scientists across the world have been heavily […]

CRISPR/HDR Platform Allows for the Production of Monoclonal Antibodies with the Constant Region of Choice

Posted Posted in Biology, Genetics

By Sharon Yang, Cell Biology, ‘20 Author’s Note: I first came across an article talking about this new innovation on Science X. Having worked with hybridomas and antibodies through various internships, I was deeply intrigued by this discovery and secured an original paper to learn more about its potential applications. Because of the revolutionizing usage of antibodies in the medical […]

The Effect of Trastuzumab on HER2-Signaling in Breast Cancers to Induce Cardiotoxicity

Posted Posted in Biology, Book Review, Genetics, News

By Karissa Cruz, B.S. Biochemistry and Molecular Biology, Spring ‘19 Author’s Note: I wrote this piece as part of my UWP 104F assignments and ended up becoming really interested in what I wrote about. I specifically chose this topic because I think breast cancer is a smart, complex disease, and the treatment can change day-to-day. I wanted to shed light […]

CRISPR: Are We Ready For It?

Posted Posted in Biology, Book Review, Genetics

By Tannavee Kumar, Genetics and Genomics, ’20 Author’s Note: When I found out that CRISPR was used for the first time on human embryos that were fully brought to term, I was pretty surprised that such a new technology with numerous unknowns was being used on the germline. I was interested in understanding the reasoning for such an experiment and what […]

Are Children Fighting The “Fat” Gene? An Analysis of Pediatric Obesity and Genetics

Posted Posted in Biology, Book Review, Genetics, Health and Medicine

By Peggy Palsgaard Author’s Note: I wrote this literature review for my UWP 104F class, and I specifically chose this topic because obesity is a very stigmatized disorder or “disease” (as the AAMC recently labeled it). I wanted to explore the link to genetics and to see how thoroughly we understand the underlying causes of obesity, specifically in children. Further, […]

Epigenetic Approach Sheds Light on Potential New Therapeutic Strategy for Alzheimer’s Disease

Posted Posted in Biology, Genetics, News

By Rachel Hull, Biochemistry & Molecular Biology, ’19 Author’s note: I first learned about this news through an article on Big Think that provided few details about the science behind the breakthrough. Reading the original research paper clarified both how this research had been conducted and what was so noteworthy about it. Given the prevalence of Alzheimer’s disease, this new […]

Cause of Seizures in Individuals with Angelman Syndrome

Posted Posted in Biology, Genetics, Neurobiology, News

By Neha Madugala, Cognitive Science, ‘22 Author’s Note While browsing recent scientific achievements and breaking news in the scientific community, I came across an article declaring that the 125-year-old neuroscience mystery surrounding perineuronal nets (PNNs) is finally resolved. PNNs have stumped neuroscientists for decades, yet their importance is undeniable. To understand the extent of this discovery, I read more about […]

Novel Mechanisms and Functions of Protein Kinase D in the Cardiovascular System

Posted Posted in Biology, Genetics, Health and Medicine

By Anna Kirillova, Genetics & Genomics ‘19   Author’s Note: I am currently studying the signaling of Protein Kinase D in cardiomyocytes as a part of my senior thesis research project. Writing this review helped me understand the known mechanisms and the techniques used to perform functional assessments of the molecule. I learned how to review literature to find key […]