By Nicole Strossman, Biochemistry & Molecular Biology, ‘17 Author’s Note: “I chose to write this review for my UWP 104F after reading about potential treatments for Alzheimer’s Disease. As this is a disease that affects such a wide variety of people, and currently has no cure, I wanted to educate myself about the developments regarding it. Although the potential treatments are still under investigation, they provide hope for people affected by a currently incurable disease.”
By David Ivanov, Biochemistry and Molecular Biology, ’15 A group of researchers studying brain cells have found a new potential target for pharmacological therapies that may help treat Alzheimer’s disease. Beta amyloid plaque, which appears to be a toxic build up of fragments of amyloid precursor protein (APP) in the brain, has long been associated with Alzheimer’s disease, and has been one of the major targets for Alzheimer’s treatment. Amyloid precursor protein plays an important role in the brain, and when this protein is broken down in nerve cells the toxic byproduct beta amyloid is formed.