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Data Reproducibility: The Chink in Science’s Armor

By Christopher Fiscus, Biotechnology, 2015

Science is an additive discipline in which each novel contribution builds upon the breadth of existing scientific knowledge and acts as a launch pad from which to pursue further study.  The scientific community is currently in the midst of a crisis: many studies are not reproducible, meaning that results cannot be adequately verified by other scientists.  According to estimates, approximately 75-90% of preclinical studies published in high-impact journals, such as Science and Nature, cannot be replicated (Begley and Ioannidis 2015).  This lack of reproducibility undermines science as a vehicle for human progress as it means that new research avenues are being pursued based on presumptive hypotheses and unverifiable findings.  The result is a widespread waste of resources, a loss of public trust in the scientific establishment, and a reduced applicability of science as a tool to better the quality of human life.  Potential solutions to this crisis include improving researcher training, employing more rigorous peer review, and increasing the transparency of scientific literature.      Continue reading Data Reproducibility: The Chink in Science’s Armor