Amoebiasis is one of the leading causes of death from parasitic disease worldwide, but it is rarely heard about in the United States. The disease is caused by a protist, specifically an amoebozoa named Entamoeba histolytica. Infection by this parasite is most common in underdeveloped countries and invades hosts by the fecal-oral route, secreting enzymes and using its pseudopods to tear apart human cells in the gastrointestinal tract. In some cases, they can penetrate the gut lining and migrate through the bloodstream to other vital organs. This can lead to bloody diarrhea, as well as abscesses in the liver, lungs, or brain, which may ultimately result in death.