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Biochemistry

Neonicotinoid Insecticide Imidacloprid: Presence in Freshwater Systems, Phytoremediation, and Bacterial Remediation

One of the most extensively used insecticides is imidacloprid, which functions by inhibiting the central nervous system in insects. That mechanism is indiscriminate, so while it harms pest species, it also harms other biota. Current research indicates that imidacloprid is infiltrating freshwater systems as a result of agricultural runoff, adversely affecting both the aquatic environment and persisting into human drinking water. This review will provide an overview of the extent to which imidacloprid pollutes freshwater systems and discuss the efficacy and viability of two sustainable methods of removing it: plant and bacterial remediation.

Intracellular, Extracellular, and Cytotoxic Effects Of Abrus Agglutinin On Tumor Cells: A Comprehensive Review

The plant molecule Abrus agglutinin (AGG) is a promising anti-tumor molecule that has been shown to increase pro-apoptotic—or pro-death—biomolecules and decrease proliferative ones in multiple different cancer cell lines. Another main benefit to AGG in potential cancer treatment is its selectiveness. In mice, AGG did not show any toxic side effects at 1mg/kg and below, and at this dose, AGG still successfully targeted cancerous cells without harming normal cells. This review confirms the potential of AGG as a chemotherapeutic agent through intracellular and extracellular methods and selective cytotoxicity.

Abnormal Salmonid Otolith Mineralogy and its Implication for Hatchery Fish Health

Over 100 million hatchery fish, in the US alone, are used to compensate for dwindling wild salmon populations. However, hatchery-rearing techniques result in physical abnormalities such as abnormal mineralogy of otoliths, which aid in fish balance, orientation and hearing. This review will assess the proposed causes of such conditions and discuss their impacts on hatchery salmonid health and salmonid research.

Exposure to Bisphenol A and Its Concentration Levels In Relation to Polycystic Ovary Syndrome

Polycystic Ovary Syndrome (PCOS) is one of the most common disorders diagnosed in women. It is characterized by menstrual irregularities, hyperandrogenism, and infertility. A solidified reason as to why so many women develop PCOS has not yet been identified, but research suggests a significant connection with Endocrine Disrupting Chemicals (EDCs). This review will examine the relationship between PCOS onset and bodily concentrations of one EDC: Bisphenol A.

Advancing Bio-Based Alternatives to UV Gel Nail Products

The beauty industry has witnessed a growing concern regarding the environmental impact of conventional nail polish formulations, particularly, those containing fossil fuel-based polymers and harmful chemicals. The search for eco-friendly alternatives has led to the exploration of bio-based polymers derived from natural resources, such as plant oils, plant starches, and bio-based monomers. This review focuses on six bio-based polymer alternatives that have shown promise in gel nail polish formulations.

What do scaling laws tell us about the biochemistry of life beyond Earth?

Humanity has always been intrigued with the possibility of life existing elsewhere in the universe. In 1977, NASA attached the Golden Record, a detailed account of humanity and Earth, onto the Voyager 1 and 2 space probes [1]. They intended for the records to be a way to share human knowledge with intelligent life forms that may stumble upon the space probes in interstellar ...

Cofactor Effects in Saccharomyces Cerevisiae Metabolism

In December of 2016, Walters, et al. released a scientific article detailing the discovery of mRNA that were capped by nicotinamide adenosine dinucleotide (NAD). Typically, mRNA are capped at the 5’ end by an adenine triphosphate (ATP) molecule, which provides a signal to RNA polymerase II that allows for the initiation of transcription. When studying the mRNAs of ...

SV2A is a Galactose Transporter

SV2A is a synaptic vesicle protein, which participates in the regulation of neurotransmitter release in humans. SV2A is expressed in neurons and endocrine cells. The exact function of SV2A is still unknown, but it has been identified that SV2A is the binding site for the antiepileptic drug, levetiracetam. Levetiracetam reduces presynaptic glutamate release, especially in neurons with high frequency firing.