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Nanoparticle Delivery of siRNA in Lung Cancer Treatments

Introduction

Lung cancer accounts for the highest mortality rate out of all cancer types (Siegel et al., 2021) due to late diagnosis and poor prognosis. Lung cancer can be classified into non-small cell lung carcinoma (NSCLC) and small cell lung carcinoma (SCLC). NSCLC accounts for 80-85% of lung cancers and is subdivided into adenocarcinoma, squamous cell carcinoma, and large cell carcinoma (Osmani et al., 2018). Common treatments for cancer include chemotherapy or radiotherapy.